| Spokane Valley to Siloam Springs (Arkansas) | 1,402.68 mi (2,257.39 km) |
| Spokane Valley to Silver Firs (Washington) | 228.66 mi (368.00 km) |
| Spokane Valley to Silver Spring (Maryland) | 2,081.75 mi (3,350.25 km) |
| Spokane Valley to Silver Springs Shores (Florida) | 2,267.94 mi (3,649.90 km) |
| Spokane Valley to Silverdale (Washington) | 253.47 mi (407.91 km) |
| Spokane Valley to Silverton (Oregon) | 322.02 mi (518.23 km) |
| Spokane Valley to Simi Valley (California) | 928.91 mi (1,494.94 km) |
| Spokane Valley to Simpsonville (South Carolina) | 2,003.46 mi (3,224.26 km) |
| Spokane Valley to Sioux City (Iowa) | 1,073.83 mi (1,728.17 km) |
| Spokane Valley to Sioux Falls (South Dakota) | 1,027.83 mi (1,654.13 km) |
| Spokane Valley to Skokie (Illinois) | 1,486.19 mi (2,391.79 km) |
| Spokane Valley to Sleepy Hollow (New York) | 2,159.40 mi (3,475.22 km) |
| Spokane Valley to Slidell (Louisiana) | 1,883.87 mi (3,031.80 km) |
| Spokane Valley to Smithfield (North Carolina) | 2,149.91 mi (3,459.95 km) |
| Spokane Valley to Smithfield (Utah) | 481.96 mi (775.65 km) |
