| Spokane Valley to Southchase (Florida) | 2,330.44 mi (3,750.48 km) |
| Spokane Valley to Southern Pines (North Carolina) | 2,114.34 mi (3,402.69 km) |
| Spokane Valley to Southfield (Michigan) | 1,681.80 mi (2,706.60 km) |
| Spokane Valley to Southgate (Michigan) | 1,692.09 mi (2,723.16 km) |
| Spokane Valley to Southlake (Texas) | 1,458.84 mi (2,347.77 km) |
| Spokane Valley to Spanaway (Washington) | 245.82 mi (395.61 km) |
| Spokane Valley to Spanish Fork (Utah) | 591.14 mi (951.35 km) |
| Spokane Valley to Spanish Lake (Missouri) | 1,482.46 mi (2,385.78 km) |
| Spokane Valley to Spanish Springs (Nevada) | 566.30 mi (911.37 km) |
| Spokane Valley to Sparks (Nevada) | 572.43 mi (921.24 km) |
| Spokane Valley to Spartanburg (South Carolina) | 2,009.53 mi (3,234.02 km) |
| Spokane Valley to Spearfish (South Dakota) | 678.43 mi (1,091.82 km) |
| Spokane Valley to Speedway (Indiana) | 1,626.93 mi (2,618.30 km) |
| Spokane Valley to Spencer (Iowa) | 1,111.34 mi (1,788.53 km) |
| Spokane Valley to Spokane (Washington) | 9.24 mi (14.87 km) |
