| Spoleto to Imola | 120.55 mi (194.00 km) |
| Spoleto to Impruneta | 96.56 mi (155.40 km) |
| Spoleto to Induno Olona | 286.23 mi (460.64 km) |
| Spoleto to Inverigo | 267.86 mi (431.09 km) |
| Spoleto to Inveruno | 269.28 mi (433.36 km) |
| Spoleto to Inzago | 248.99 mi (400.70 km) |
| Spoleto to Iseo | 239.13 mi (384.84 km) |
| Spoleto to Isernia | 112.63 mi (181.26 km) |
| Spoleto to Isola Capo Rizzuto | 349.12 mi (561.86 km) |
| Spoleto to Isola del Liri | 87.18 mi (140.30 km) |
| Spoleto to Isola della Scala | 192.52 mi (309.82 km) |
| Spoleto to Isola Vicentina | 207.97 mi (334.70 km) |
| Spoleto to Ispica | 429.09 mi (690.56 km) |
| Spoleto to Istrana | 204.29 mi (328.77 km) |
| Spoleto to Itri | 110.70 mi (178.15 km) |
