| Cities | Distance |
|---|---|
| Spoleto to Sestu | 303.48 mi (488.41 km) |
| Spoleto to Settimo Torinese | 294.61 mi (474.13 km) |
| Spoleto to Seveso | 265.79 mi (427.75 km) |
| Spoleto to Sezze | 88.99 mi (143.21 km) |
| Spoleto to Siano | 170.11 mi (273.76 km) |
| Spoleto to Siena | 78.63 mi (126.54 km) |
| Spoleto to Signa | 106.75 mi (171.79 km) |
| Spoleto to Silea | 201.17 mi (323.75 km) |
| Spoleto to Silvi Paese | 74.11 mi (119.27 km) |
| Spoleto to Sinalunga | 57.68 mi (92.83 km) |
| Spoleto to Siniscola | 215.70 mi (347.13 km) |
| Spoleto to Sinnai | 299.76 mi (482.42 km) |
| Spoleto to Siracusa | 416.39 mi (670.11 km) |
| Spoleto to Solaro | 266.12 mi (428.28 km) |
| Spoleto to Soliera | 162.69 mi (261.83 km) |