| Spoleto to Ericeira | 1,180.75 mi (1,900.24 km) |
| Spoleto to Ermezinde | 1,092.86 mi (1,758.78 km) |
| Spoleto to Esmoriz | 1,100.87 mi (1,771.67 km) |
| Spoleto to Espinho | 1,100.64 mi (1,771.31 km) |
| Spoleto to Esposende | 1,100.09 mi (1,770.43 km) |
| Spoleto to Estarreja | 1,101.21 mi (1,772.23 km) |
| Spoleto to Estoril | 1,185.94 mi (1,908.59 km) |
| Spoleto to Estremoz | 1,090.95 mi (1,755.71 km) |
| Spoleto to Evora | 1,113.95 mi (1,792.73 km) |
| Spoleto to Fafe | 1,070.01 mi (1,722.01 km) |
| Spoleto to Falagueira | 1,175.92 mi (1,892.46 km) |
| Spoleto to Famalicao | 1,088.23 mi (1,751.33 km) |
| Spoleto to Fanzeres | 1,092.78 mi (1,758.65 km) |
| Spoleto to Faro | 1,159.32 mi (1,865.75 km) |
| Spoleto to Fatima | 1,127.82 mi (1,815.06 km) |
