| Spoleto to Santiago do Cacem | 1,168.51 mi (1,880.54 km) |
| Spoleto to Santo Andre | 1,170.12 mi (1,883.13 km) |
| Spoleto to Santo Tirso | 1,086.90 mi (1,749.20 km) |
| Spoleto to Sao Bras de Alportel | 1,152.68 mi (1,855.06 km) |
| Spoleto to Sao Felix da Marinha | 1,099.40 mi (1,769.31 km) |
| Spoleto to Sao Joao da Madeira | 1,094.80 mi (1,761.92 km) |
| Spoleto to Sao Joao de Ver | 1,097.03 mi (1,765.49 km) |
| Spoleto to Sao Mamede de Infesta | 1,095.65 mi (1,763.28 km) |
| Spoleto to Sao Pedro do Sul | 1,075.85 mi (1,731.41 km) |
| Spoleto to Satao | 1,059.22 mi (1,704.65 km) |
| Spoleto to Seia | 1,063.17 mi (1,711.01 km) |
| Spoleto to Senhora da Hora | 1,098.45 mi (1,767.78 km) |
| Spoleto to Serpa | 1,115.44 mi (1,795.13 km) |
| Spoleto to Serta | 1,095.50 mi (1,763.04 km) |
| Spoleto to Sesimbra | 1,177.38 mi (1,894.82 km) |
