| Spoleto to Sangeorz-Bai | 665.50 mi (1,071.01 km) |
| Spoleto to Sannicolau Mare | 452.77 mi (728.67 km) |
| Spoleto to Santana | 499.57 mi (803.98 km) |
| Spoleto to Satu Mare | 605.12 mi (973.84 km) |
| Spoleto to Scobinti | 763.71 mi (1,229.08 km) |
| Spoleto to Scornicesti | 605.53 mi (974.50 km) |
| Spoleto to Sebes | 580.86 mi (934.80 km) |
| Spoleto to Seini | 619.43 mi (996.88 km) |
| Spoleto to Sfantu-Gheorghe | 681.48 mi (1,096.73 km) |
| Spoleto to Sibiu | 604.13 mi (972.25 km) |
| Spoleto to Sighetu Marmatiei | 650.09 mi (1,046.22 km) |
| Spoleto to Sighisoara | 641.99 mi (1,033.19 km) |
| Spoleto to Simeria | 552.92 mi (889.84 km) |
| Spoleto to Sinaia | 662.71 mi (1,066.53 km) |
| Spoleto to Slatina | 595.19 mi (957.87 km) |
