| Spoleto to Olympia Heights (Florida) | 5,178.14 mi (8,333.40 km) |
| Spoleto to Omaha (Nebraska) | 5,134.35 mi (8,262.93 km) |
| Spoleto to On Top of the World Designated Place (Florida) | 5,117.08 mi (8,235.14 km) |
| Spoleto to Onalaska (Wisconsin) | 4,829.95 mi (7,773.05 km) |
| Spoleto to Oneida (New York) | 4,240.36 mi (6,824.20 km) |
| Spoleto to Oneonta (New York) | 4,238.67 mi (6,821.48 km) |
| Spoleto to Ontario (California) | 6,271.65 mi (10,093.24 km) |
| Spoleto to Ontario (Oregon) | 5,682.91 mi (9,145.76 km) |
| Spoleto to Opa-locka (Florida) | 5,166.29 mi (8,314.33 km) |
| Spoleto to Opelika (Alabama) | 5,096.25 mi (8,201.63 km) |
| Spoleto to Opelousas (Louisiana) | 5,487.41 mi (8,831.14 km) |
| Spoleto to Orange (California) | 6,292.04 mi (10,126.07 km) |
| Spoleto to Orange (Texas) | 5,578.67 mi (8,978.00 km) |
| Spoleto to Orange City (Florida) | 5,078.73 mi (8,173.43 km) |
| Spoleto to Orangeburg (South Carolina) | 4,858.97 mi (7,819.76 km) |
