| Spring Creek to Southchase (Florida) | 2,108.47 mi (3,393.25 km) |
| Spring Creek to Southern Pines (North Carolina) | 1,993.84 mi (3,208.78 km) |
| Spring Creek to Southfield (Michigan) | 1,664.70 mi (2,679.07 km) |
| Spring Creek to Southgate (Michigan) | 1,669.84 mi (2,687.34 km) |
| Spring Creek to Southlake (Texas) | 1,150.01 mi (1,850.76 km) |
| Spring Creek to Spanaway (Washington) | 554.55 mi (892.47 km) |
| Spring Creek to Spanish Fork (Utah) | 212.71 mi (342.33 km) |
| Spring Creek to Spanish Lake (Missouri) | 1,350.49 mi (2,173.40 km) |
| Spring Creek to Spanish Springs (Nevada) | 227.59 mi (366.27 km) |
| Spring Creek to Sparks (Nevada) | 231.99 mi (373.34 km) |
| Spring Creek to Spartanburg (South Carolina) | 1,868.37 mi (3,006.86 km) |
| Spring Creek to Spearfish (South Dakota) | 651.82 mi (1,049.00 km) |
| Spring Creek to Speedway (Indiana) | 1,541.50 mi (2,480.80 km) |
| Spring Creek to Spencer (Iowa) | 1,060.95 mi (1,707.44 km) |
| Spring Creek to Spokane (Washington) | 486.79 mi (783.41 km) |
