| Street to Spello | 914.57 mi (1,471.86 km) |
| Street to Spilamberto | 781.83 mi (1,258.23 km) |
| Street to Spilimbergo | 790.47 mi (1,272.14 km) |
| Street to Spinea | 785.39 mi (1,263.97 km) |
| Street to Spoleto | 926.13 mi (1,490.46 km) |
| Street to Spoltore | 994.20 mi (1,600.01 km) |
| Street to Spresiano | 777.63 mi (1,251.48 km) |
| Street to Squinzano | 1,237.43 mi (1,991.44 km) |
| Street to Statte | 1,198.84 mi (1,929.34 km) |
| Street to Stezzano | 681.43 mi (1,096.65 km) |
| Street to Strada | 836.80 mi (1,346.69 km) |
| Street to Stradella | 693.32 mi (1,115.80 km) |
| Street to Striano | 1,089.56 mi (1,753.48 km) |
| Street to Subiaco | 981.25 mi (1,579.16 km) |
| Street to Sulmona | 1,005.66 mi (1,618.45 km) |
