| Tampa to Santa Paula (California) | 2,196.75 mi (3,535.33 km) |
| Tampa to Santa Rosa (California) | 2,415.33 mi (3,887.09 km) |
| Tampa to Santaquin (Utah) | 1,862.29 mi (2,997.06 km) |
| Tampa to Santee (California) | 2,075.75 mi (3,340.60 km) |
| Tampa to Sapulpa (Oklahoma) | 971.45 mi (1,563.40 km) |
| Tampa to Saraland (Alabama) | 393.26 mi (632.89 km) |
| Tampa to Sarasota (Florida) | 45.71 mi (73.56 km) |
| Tampa to Sarasota Springs (Florida) | 47.42 mi (76.31 km) |
| Tampa to Saratoga (California) | 2,371.89 mi (3,817.19 km) |
| Tampa to Saratoga Springs (New York) | 1,148.24 mi (1,847.92 km) |
| Tampa to Saratoga Springs (Utah) | 1,876.20 mi (3,019.45 km) |
| Tampa to Sartell (Minnesota) | 1,377.56 mi (2,216.97 km) |
| Tampa to Satellite Beach (Florida) | 113.04 mi (181.93 km) |
| Tampa to Sauk Rapids (Minnesota) | 1,374.64 mi (2,212.27 km) |
| Tampa to Sault Ste. Marie (Michigan) | 1,281.63 mi (2,062.58 km) |
