| Tampa to Scottsbluff (Nebraska) | 1,529.83 mi (2,462.03 km) |
| Tampa to Scottsboro (Alabama) | 506.18 mi (814.62 km) |
| Tampa to Scottsdale (Arizona) | 1,782.61 mi (2,868.84 km) |
| Tampa to Scranton (Pennsylvania) | 1,002.53 mi (1,613.42 km) |
| Tampa to Seabrook (Maryland) | 824.20 mi (1,326.42 km) |
| Tampa to Seabrook (Texas) | 769.11 mi (1,237.76 km) |
| Tampa to Seaford (New York) | 1,012.39 mi (1,629.28 km) |
| Tampa to Seagoville (Texas) | 899.53 mi (1,447.65 km) |
| Tampa to Seal Beach (California) | 2,139.02 mi (3,442.42 km) |
| Tampa to Searcy (Arkansas) | 740.61 mi (1,191.90 km) |
| Tampa to Seaside (California) | 2,357.78 mi (3,794.48 km) |
| Tampa to SeaTac (Washington) | 2,519.63 mi (4,054.95 km) |
| Tampa to Seattle (Washington) | 2,524.53 mi (4,062.84 km) |
| Tampa to Sebastian (Florida) | 120.76 mi (194.34 km) |
| Tampa to Sebring (Florida) | 70.40 mi (113.30 km) |
