| Tampa to Southchase (Florida) | 69.50 mi (111.85 km) |
| Tampa to Southern Pines (North Carolina) | 528.48 mi (850.50 km) |
| Tampa to Southfield (Michigan) | 1,001.65 mi (1,612.01 km) |
| Tampa to Southgate (Michigan) | 982.76 mi (1,581.60 km) |
| Tampa to Southlake (Texas) | 939.27 mi (1,511.60 km) |
| Tampa to Spanaway (Washington) | 2,517.99 mi (4,052.32 km) |
| Tampa to Spanish Fork (Utah) | 1,857.43 mi (2,989.25 km) |
| Tampa to Spanish Lake (Missouri) | 869.07 mi (1,398.64 km) |
| Tampa to Spanish Springs (Nevada) | 2,264.12 mi (3,643.74 km) |
| Tampa to Sparks (Nevada) | 2,265.65 mi (3,646.21 km) |
| Tampa to Spartanburg (South Carolina) | 481.15 mi (774.34 km) |
| Tampa to Spearfish (South Dakota) | 1,638.84 mi (2,637.47 km) |
| Tampa to Speedway (Indiana) | 843.69 mi (1,357.78 km) |
| Tampa to Spencer (Iowa) | 1,264.08 mi (2,034.34 km) |
| Tampa to Spokane (Washington) | 2,312.65 mi (3,721.84 km) |
