| Targu Secuiesc to Sacile | 654.11 mi (1,052.70 km) |
| Targu Secuiesc to Sala Consilina | 655.91 mi (1,055.59 km) |
| Targu Secuiesc to Salemi | 886.76 mi (1,427.11 km) |
| Targu Secuiesc to Salerno | 678.71 mi (1,092.27 km) |
| Targu Secuiesc to Salo | 751.11 mi (1,208.80 km) |
| Targu Secuiesc to Salsomaggiore Terme | 786.83 mi (1,266.27 km) |
| Targu Secuiesc to Saluzzo | 908.74 mi (1,462.48 km) |
| Targu Secuiesc to Salzano | 675.83 mi (1,087.64 km) |
| Targu Secuiesc to Samarate | 834.75 mi (1,343.39 km) |
| Targu Secuiesc to San Benedetto del Tronto | 639.15 mi (1,028.61 km) |
| Targu Secuiesc to San Biagio di Callalta | 661.79 mi (1,065.05 km) |
| Targu Secuiesc to San Bonifacio | 717.11 mi (1,154.08 km) |
| Targu Secuiesc to San Casciano in Val di Pesa | 749.25 mi (1,205.81 km) |
| Targu Secuiesc to San Cataldo | 857.76 mi (1,380.44 km) |
| Targu Secuiesc to San Cesareo | 723.00 mi (1,163.56 km) |
