| Targu Secuiesc to Sestu | 979.41 mi (1,576.21 km) |
| Targu Secuiesc to Settimo Torinese | 888.80 mi (1,430.39 km) |
| Targu Secuiesc to Seveso | 817.55 mi (1,315.71 km) |
| Targu Secuiesc to Sezze | 721.56 mi (1,161.23 km) |
| Targu Secuiesc to Siano | 676.49 mi (1,088.71 km) |
| Targu Secuiesc to Siena | 749.77 mi (1,206.64 km) |
| Targu Secuiesc to Signa | 750.74 mi (1,208.20 km) |
| Targu Secuiesc to Silea | 666.12 mi (1,072.02 km) |
| Targu Secuiesc to Silvi Paese | 639.93 mi (1,029.87 km) |
| Targu Secuiesc to Sinalunga | 733.12 mi (1,179.84 km) |
| Targu Secuiesc to Siniscola | 905.74 mi (1,457.64 km) |
| Targu Secuiesc to Sinnai | 974.34 mi (1,568.05 km) |
| Targu Secuiesc to Siracusa | 832.49 mi (1,339.76 km) |
| Targu Secuiesc to Solaro | 820.38 mi (1,320.27 km) |
| Targu Secuiesc to Soliera | 742.57 mi (1,195.05 km) |
