| Targu Secuiesc to Spello | 694.59 mi (1,117.83 km) |
| Targu Secuiesc to Spilamberto | 741.24 mi (1,192.91 km) |
| Targu Secuiesc to Spilimbergo | 634.83 mi (1,021.66 km) |
| Targu Secuiesc to Spinea | 674.10 mi (1,084.86 km) |
| Targu Secuiesc to Spoleto | 700.15 mi (1,126.78 km) |
| Targu Secuiesc to Spoltore | 641.77 mi (1,032.84 km) |
| Targu Secuiesc to Spresiano | 667.34 mi (1,073.97 km) |
| Targu Secuiesc to Squinzano | 559.59 mi (900.57 km) |
| Targu Secuiesc to Statte | 585.03 mi (941.51 km) |
| Targu Secuiesc to Stezzano | 792.81 mi (1,275.90 km) |
| Targu Secuiesc to Strada | 744.58 mi (1,198.29 km) |
| Targu Secuiesc to Stradella | 815.89 mi (1,313.04 km) |
| Targu Secuiesc to Striano | 681.34 mi (1,096.52 km) |
| Targu Secuiesc to Subiaco | 705.59 mi (1,135.54 km) |
| Targu Secuiesc to Sulmona | 664.44 mi (1,069.31 km) |
