| Upton to Sestu | 1,130.16 mi (1,818.82 km) |
| Upton to Settimo Torinese | 750.08 mi (1,207.13 km) |
| Upton to Seveso | 764.47 mi (1,230.29 km) |
| Upton to Sezze | 1,110.67 mi (1,787.45 km) |
| Upton to Siano | 1,200.29 mi (1,931.67 km) |
| Upton to Siena | 957.13 mi (1,540.35 km) |
| Upton to Signa | 924.82 mi (1,488.36 km) |
| Upton to Silea | 869.94 mi (1,400.03 km) |
| Upton to Silvi Paese | 1,087.76 mi (1,750.58 km) |
| Upton to Sinalunga | 975.22 mi (1,569.47 km) |
| Upton to Siniscola | 1,067.57 mi (1,718.09 km) |
| Upton to Sinnai | 1,132.64 mi (1,822.80 km) |
| Upton to Siracusa | 1,430.35 mi (2,301.93 km) |
| Upton to Solaro | 764.25 mi (1,229.94 km) |
| Upton to Soliera | 868.94 mi (1,398.42 km) |
