| Valdepenas to Sestu | 670.92 mi (1,079.74 km) |
| Valdepenas to Settimo Torinese | 721.90 mi (1,161.79 km) |
| Valdepenas to Seveso | 796.89 mi (1,282.47 km) |
| Valdepenas to Sezze | 888.64 mi (1,430.14 km) |
| Valdepenas to Siano | 969.19 mi (1,559.75 km) |
| Valdepenas to Siena | 828.14 mi (1,332.76 km) |
| Valdepenas to Signa | 827.37 mi (1,331.53 km) |
| Valdepenas to Silea | 931.26 mi (1,498.72 km) |
| Valdepenas to Silvi Paese | 952.64 mi (1,533.12 km) |
| Valdepenas to Sinalunga | 845.48 mi (1,360.67 km) |
| Valdepenas to Siniscola | 706.91 mi (1,137.67 km) |
| Valdepenas to Sinnai | 676.86 mi (1,089.31 km) |
| Valdepenas to Siracusa | 1,023.52 mi (1,647.20 km) |
| Valdepenas to Solaro | 793.66 mi (1,277.27 km) |
| Valdepenas to Soliera | 844.08 mi (1,358.42 km) |
