| Valletta to Selargius | 373.56 mi (601.18 km) |
| Valletta to Selvazzano Dentro | 670.68 mi (1,079.35 km) |
| Valletta to Senago | 725.57 mi (1,167.69 km) |
| Valletta to Senigallia | 544.28 mi (875.94 km) |
| Valletta to Seravezza | 603.69 mi (971.55 km) |
| Valletta to Seregno | 728.43 mi (1,172.30 km) |
| Valletta to Seriate | 720.84 mi (1,160.08 km) |
| Valletta to Sermoneta | 399.08 mi (642.26 km) |
| Valletta to Serramanna | 390.78 mi (628.89 km) |
| Valletta to Serravalle Pistoiese | 586.08 mi (943.21 km) |
| Valletta to Sessa Aurunca | 369.94 mi (595.35 km) |
| Valletta to Sesto Calende | 745.31 mi (1,199.46 km) |
| Valletta to Sesto Fiorentino | 575.58 mi (926.30 km) |
| Valletta to Sesto San Giovanni | 720.42 mi (1,159.41 km) |
| Valletta to Sestri Levante | 638.47 mi (1,027.52 km) |
