| Valletta to Solofra | 341.46 mi (549.53 km) |
| Valletta to Somma Lombardo | 740.79 mi (1,192.19 km) |
| Valletta to Somma Vesuviana | 343.71 mi (553.14 km) |
| Valletta to Sommacampagna | 683.80 mi (1,100.47 km) |
| Valletta to Sona | 686.24 mi (1,104.39 km) |
| Valletta to Sondrio | 749.45 mi (1,206.12 km) |
| Valletta to Sora | 404.89 mi (651.60 km) |
| Valletta to Sorbolo | 653.98 mi (1,052.48 km) |
| Valletta to Soresina | 692.81 mi (1,114.97 km) |
| Valletta to Sorisole | 725.33 mi (1,167.31 km) |
| Valletta to Sorrento | 326.86 mi (526.04 km) |
| Valletta to Sorso | 466.73 mi (751.13 km) |
| Valletta to Sortino | 92.28 mi (148.52 km) |
| Valletta to Soverato Marina | 222.63 mi (358.29 km) |
| Valletta to Sovicille | 539.18 mi (867.72 km) |
