| Valletta to Schijndel | 1,174.61 mi (1,890.35 km) |
| Valletta to Schinnen | 1,124.67 mi (1,809.99 km) |
| Valletta to Schoonhoven | 1,206.33 mi (1,941.40 km) |
| Valletta to Simpelveld | 1,115.52 mi (1,795.25 km) |
| Valletta to Sint Anthonis | 1,166.96 mi (1,878.04 km) |
| Valletta to Sint Willebrord | 1,186.96 mi (1,910.23 km) |
| Valletta to Sint-Michielsgestel | 1,177.67 mi (1,895.27 km) |
| Valletta to Sint-Oedenrode | 1,170.79 mi (1,884.21 km) |
| Valletta to Sittard | 1,128.10 mi (1,815.50 km) |
| Valletta to Sliedrecht | 1,199.76 mi (1,930.82 km) |
| Valletta to Slochteren | 1,253.62 mi (2,017.51 km) |
| Valletta to Sluis | 1,198.37 mi (1,928.59 km) |
| Valletta to Sneek | 1,259.49 mi (2,026.96 km) |
| Valletta to Soest | 1,212.35 mi (1,951.09 km) |
| Valletta to Someren | 1,154.79 mi (1,858.46 km) |
