| Valletta to Ruzomberok | 942.38 mi (1,516.62 km) |
| Valletta to Sabinov | 971.13 mi (1,562.88 km) |
| Valletta to Sal'a | 863.74 mi (1,390.06 km) |
| Valletta to Samorin | 850.08 mi (1,368.08 km) |
| Valletta to Senec | 863.89 mi (1,390.30 km) |
| Valletta to Senica | 894.97 mi (1,440.31 km) |
| Valletta to Sered' | 871.64 mi (1,402.76 km) |
| Valletta to Skalica | 904.85 mi (1,456.21 km) |
| Valletta to Smizany | 952.16 mi (1,532.35 km) |
| Valletta to Snina | 983.59 mi (1,582.94 km) |
| Valletta to Spisska Nova Ves | 952.02 mi (1,532.13 km) |
| Valletta to Stara L'ubovna | 977.41 mi (1,572.99 km) |
| Valletta to Stara Tura | 904.33 mi (1,455.37 km) |
| Valletta to Stropkov | 987.50 mi (1,589.23 km) |
| Valletta to Stupava | 864.70 mi (1,391.60 km) |
