| Vila Nova de Gaia to Savignano sul Rubicone | 1,084.58 mi (1,745.46 km) |
| Vila Nova de Gaia to Savona | 893.36 mi (1,437.72 km) |
| Vila Nova de Gaia to Scafati | 1,204.51 mi (1,938.47 km) |
| Vila Nova de Gaia to Scalea | 1,282.32 mi (2,063.69 km) |
| Vila Nova de Gaia to Scandiano | 1,003.85 mi (1,615.53 km) |
| Vila Nova de Gaia to Scandicci | 1,023.38 mi (1,646.98 km) |
| Vila Nova de Gaia to Schio | 1,047.76 mi (1,686.20 km) |
| Vila Nova de Gaia to Sciacca | 1,183.58 mi (1,904.79 km) |
| Vila Nova de Gaia to Scicli | 1,284.00 mi (2,066.40 km) |
| Vila Nova de Gaia to Scordia | 1,279.65 mi (2,059.40 km) |
| Vila Nova de Gaia to Scorze | 1,081.99 mi (1,741.29 km) |
| Vila Nova de Gaia to Sedico | 1,088.13 mi (1,751.17 km) |
| Vila Nova de Gaia to Sedriano | 931.45 mi (1,499.03 km) |
| Vila Nova de Gaia to Segni | 1,118.76 mi (1,800.47 km) |
| Vila Nova de Gaia to Segrate | 947.10 mi (1,524.21 km) |
