| Vila Nova de Gaia to Sestu | 941.19 mi (1,514.70 km) |
| Vila Nova de Gaia to Settimo Torinese | 869.26 mi (1,398.93 km) |
| Vila Nova de Gaia to Seveso | 941.95 mi (1,515.92 km) |
| Vila Nova de Gaia to Sezze | 1,122.57 mi (1,806.60 km) |
| Vila Nova de Gaia to Siano | 1,212.73 mi (1,951.70 km) |
| Vila Nova de Gaia to Siena | 1,029.19 mi (1,656.33 km) |
| Vila Nova de Gaia to Signa | 1,019.05 mi (1,640.01 km) |
| Vila Nova de Gaia to Silea | 1,091.86 mi (1,757.18 km) |
| Vila Nova de Gaia to Silvi Paese | 1,170.73 mi (1,884.11 km) |
| Vila Nova de Gaia to Sinalunga | 1,049.26 mi (1,688.62 km) |
| Vila Nova de Gaia to Siniscola | 956.07 mi (1,538.64 km) |
| Vila Nova de Gaia to Sinnai | 946.93 mi (1,523.94 km) |
| Vila Nova de Gaia to Siracusa | 1,307.68 mi (2,104.50 km) |
| Vila Nova de Gaia to Solaro | 938.99 mi (1,511.16 km) |
| Vila Nova de Gaia to Soliera | 1,016.64 mi (1,636.12 km) |
