| Vila Nova de Gaia to Spello | 1,096.57 mi (1,764.77 km) |
| Vila Nova de Gaia to Spilamberto | 1,019.45 mi (1,640.64 km) |
| Vila Nova de Gaia to Spilimbergo | 1,125.23 mi (1,810.88 km) |
| Vila Nova de Gaia to Spinea | 1,083.62 mi (1,743.92 km) |
| Vila Nova de Gaia to Spoleto | 1,097.52 mi (1,766.29 km) |
| Vila Nova de Gaia to Spoltore | 1,172.26 mi (1,886.58 km) |
| Vila Nova de Gaia to Spresiano | 1,091.09 mi (1,755.94 km) |
| Vila Nova de Gaia to Squinzano | 1,390.49 mi (2,237.77 km) |
| Vila Nova de Gaia to Statte | 1,344.90 mi (2,164.40 km) |
| Vila Nova de Gaia to Stezzano | 966.35 mi (1,555.19 km) |
| Vila Nova de Gaia to Strada | 1,029.13 mi (1,656.22 km) |
| Vila Nova de Gaia to Stradella | 941.80 mi (1,515.67 km) |
| Vila Nova de Gaia to Striano | 1,205.98 mi (1,940.84 km) |
| Vila Nova de Gaia to Subiaco | 1,121.57 mi (1,804.99 km) |
| Vila Nova de Gaia to Sulmona | 1,163.25 mi (1,872.07 km) |
