| Vila Nova de Gaia to Ede | 1,010.71 mi (1,626.58 km) |
| Vila Nova de Gaia to Eemnes | 1,007.37 mi (1,621.20 km) |
| Vila Nova de Gaia to Eerbeek | 1,025.75 mi (1,650.78 km) |
| Vila Nova de Gaia to Eersel | 967.19 mi (1,556.54 km) |
| Vila Nova de Gaia to Eijsden | 954.75 mi (1,536.52 km) |
| Vila Nova de Gaia to Eindhoven | 976.38 mi (1,571.34 km) |
| Vila Nova de Gaia to Elburg | 1,035.22 mi (1,666.02 km) |
| Vila Nova de Gaia to Emmeloord | 1,044.62 mi (1,681.16 km) |
| Vila Nova de Gaia to Emmen | 1,083.24 mi (1,743.31 km) |
| Vila Nova de Gaia to Enkhuizen | 1,030.75 mi (1,658.83 km) |
| Vila Nova de Gaia to Enschede | 1,057.55 mi (1,701.96 km) |
| Vila Nova de Gaia to Epe | 1,034.61 mi (1,665.05 km) |
| Vila Nova de Gaia to Ermelo | 1,020.95 mi (1,643.06 km) |
| Vila Nova de Gaia to Etten-Leur | 955.67 mi (1,538.00 km) |
| Vila Nova de Gaia to Franeker | 1,062.24 mi (1,709.51 km) |
