| Vila Real de Santo Antonio to Senftenberg | 1,439.23 mi (2,316.21 km) |
| Vila Real de Santo Antonio to Siegburg | 1,183.71 mi (1,905.00 km) |
| Vila Real de Santo Antonio to Siegen | 1,212.35 mi (1,951.08 km) |
| Vila Real de Santo Antonio to Sigmaringen | 1,127.43 mi (1,814.43 km) |
| Vila Real de Santo Antonio to Simbach am Inn | 1,281.99 mi (2,063.16 km) |
| Vila Real de Santo Antonio to Simmerath | 1,146.80 mi (1,845.59 km) |
| Vila Real de Santo Antonio to Sindelfingen | 1,145.55 mi (1,843.58 km) |
| Vila Real de Santo Antonio to Sinsheim | 1,164.52 mi (1,874.11 km) |
| Vila Real de Santo Antonio to Sinzheim | 1,117.99 mi (1,799.24 km) |
| Vila Real de Santo Antonio to Sinzig | 1,172.28 mi (1,886.60 km) |
| Vila Real de Santo Antonio to Soest | 1,249.30 mi (2,010.55 km) |
| Vila Real de Santo Antonio to Solingen | 1,198.76 mi (1,929.21 km) |
| Vila Real de Santo Antonio to Soltau | 1,370.17 mi (2,205.08 km) |
| Vila Real de Santo Antonio to Sommerda | 1,324.80 mi (2,132.05 km) |
| Vila Real de Santo Antonio to Sondershausen | 1,325.63 mi (2,133.39 km) |
