| Vila Real de Santo Antonio to Orbetello | 1,050.26 mi (1,690.23 km) |
| Vila Real de Santo Antonio to Oria | 1,362.40 mi (2,192.56 km) |
| Vila Real de Santo Antonio to Oristano | 883.73 mi (1,422.22 km) |
| Vila Real de Santo Antonio to Orta Nova | 1,265.70 mi (2,036.95 km) |
| Vila Real de Santo Antonio to Orte | 1,108.83 mi (1,784.50 km) |
| Vila Real de Santo Antonio to Ortona | 1,208.15 mi (1,944.33 km) |
| Vila Real de Santo Antonio to Orvieto | 1,099.23 mi (1,769.03 km) |
| Vila Real de Santo Antonio to Orzinuovi | 1,060.76 mi (1,707.13 km) |
| Vila Real de Santo Antonio to Osimo | 1,179.31 mi (1,897.91 km) |
| Vila Real de Santo Antonio to Ospitaletto | 1,071.60 mi (1,724.58 km) |
| Vila Real de Santo Antonio to Ostuni | 1,360.30 mi (2,189.19 km) |
| Vila Real de Santo Antonio to Ottaviano | 1,198.68 mi (1,929.08 km) |
| Vila Real de Santo Antonio to Ovada | 981.18 mi (1,579.06 km) |
| Vila Real de Santo Antonio to Ozieri | 912.04 mi (1,467.79 km) |
| Vila Real de Santo Antonio to Paceco | 1,092.40 mi (1,758.05 km) |
