| Vila Real de Santo Antonio to Ede | 1,207.28 mi (1,942.92 km) |
| Vila Real de Santo Antonio to Eemnes | 1,207.98 mi (1,944.06 km) |
| Vila Real de Santo Antonio to Eerbeek | 1,220.52 mi (1,964.24 km) |
| Vila Real de Santo Antonio to Eersel | 1,159.68 mi (1,866.33 km) |
| Vila Real de Santo Antonio to Eijsden | 1,139.33 mi (1,833.58 km) |
| Vila Real de Santo Antonio to Eindhoven | 1,168.62 mi (1,880.72 km) |
| Vila Real de Santo Antonio to Elburg | 1,234.06 mi (1,986.03 km) |
| Vila Real de Santo Antonio to Emmeloord | 1,246.07 mi (2,005.36 km) |
| Vila Real de Santo Antonio to Emmen | 1,279.13 mi (2,058.56 km) |
| Vila Real de Santo Antonio to Enkhuizen | 1,234.60 mi (1,986.90 km) |
| Vila Real de Santo Antonio to Enschede | 1,248.65 mi (2,009.51 km) |
| Vila Real de Santo Antonio to Epe | 1,231.90 mi (1,982.55 km) |
| Vila Real de Santo Antonio to Ermelo | 1,219.88 mi (1,963.20 km) |
| Vila Real de Santo Antonio to Etten-Leur | 1,154.28 mi (1,857.63 km) |
| Vila Real de Santo Antonio to Franeker | 1,268.54 mi (2,041.51 km) |
