| Villafranca de los Barros to Spello | 1,037.63 mi (1,669.91 km) |
| Villafranca de los Barros to Spilamberto | 984.70 mi (1,584.72 km) |
| Villafranca de los Barros to Spilimbergo | 1,107.73 mi (1,782.71 km) |
| Villafranca de los Barros to Spinea | 1,059.53 mi (1,705.16 km) |
| Villafranca de los Barros to Spoleto | 1,035.44 mi (1,666.38 km) |
| Villafranca de los Barros to Spoltore | 1,105.52 mi (1,779.16 km) |
| Villafranca de los Barros to Spresiano | 1,070.67 mi (1,723.08 km) |
| Villafranca de los Barros to Squinzano | 1,302.19 mi (2,095.68 km) |
| Villafranca de los Barros to Statte | 1,257.27 mi (2,023.37 km) |
| Villafranca de los Barros to Stezzano | 951.90 mi (1,531.93 km) |
| Villafranca de los Barros to Strada | 980.11 mi (1,577.34 km) |
| Villafranca de los Barros to Stradella | 920.03 mi (1,480.64 km) |
| Villafranca de los Barros to Striano | 1,119.28 mi (1,801.31 km) |
| Villafranca de los Barros to Subiaco | 1,048.40 mi (1,687.24 km) |
| Villafranca de los Barros to Sulmona | 1,091.44 mi (1,756.50 km) |
