| Webster Groves to Enterprise (Nevada) | 1,374.41 mi (2,211.90 km) |
| Webster Groves to Enumclaw (Washington) | 1,694.32 mi (2,726.74 km) |
| Webster Groves to Ephrata (Pennsylvania) | 764.02 mi (1,229.58 km) |
| Webster Groves to Erie (Colorado) | 790.52 mi (1,272.22 km) |
| Webster Groves to Erie (Pennsylvania) | 593.23 mi (954.72 km) |
| Webster Groves to Erlanger (Kentucky) | 311.92 mi (501.99 km) |
| Webster Groves to Escanaba (Michigan) | 522.14 mi (840.30 km) |
| Webster Groves to Escondido (California) | 1,536.81 mi (2,473.25 km) |
| Webster Groves to Española (New Mexico) | 880.79 mi (1,417.50 km) |
| Webster Groves to Essex (Maryland) | 748.36 mi (1,204.37 km) |
| Webster Groves to Essex Junction (Vermont) | 977.94 mi (1,573.84 km) |
| Webster Groves to Estelle (Louisiana) | 604.18 mi (972.33 km) |
| Webster Groves to Estero (Florida) | 975.86 mi (1,570.50 km) |
| Webster Groves to Euclid (Ohio) | 510.75 mi (821.98 km) |
| Webster Groves to Eufaula (Alabama) | 546.58 mi (879.63 km) |
