| Webster Groves to Santa Paula (California) | 1,615.00 mi (2,599.09 km) |
| Webster Groves to Santa Rosa (California) | 1,739.84 mi (2,800.01 km) |
| Webster Groves to Santaquin (Utah) | 1,147.87 mi (1,847.32 km) |
| Webster Groves to Santee (California) | 1,539.40 mi (2,477.43 km) |
| Webster Groves to Sapulpa (Oklahoma) | 362.46 mi (583.32 km) |
| Webster Groves to Saraland (Alabama) | 549.75 mi (884.73 km) |
| Webster Groves to Sarasota (Florida) | 898.57 mi (1,446.11 km) |
| Webster Groves to Sarasota Springs (Florida) | 902.39 mi (1,452.26 km) |
| Webster Groves to Saratoga (California) | 1,719.97 mi (2,768.03 km) |
| Webster Groves to Saratoga Springs (New York) | 918.41 mi (1,478.04 km) |
| Webster Groves to Saratoga Springs (Utah) | 1,153.59 mi (1,856.52 km) |
| Webster Groves to Sartell (Minnesota) | 524.58 mi (844.23 km) |
| Webster Groves to Satellite Beach (Florida) | 911.88 mi (1,467.53 km) |
| Webster Groves to Sauk Rapids (Minnesota) | 521.98 mi (840.05 km) |
| Webster Groves to Sault Ste. Marie (Michigan) | 624.32 mi (1,004.74 km) |
