| Webster Groves to Sunset (Florida) | 1,063.47 mi (1,711.48 km) |
| Webster Groves to Superior (Colorado) | 796.52 mi (1,281.87 km) |
| Webster Groves to Superior (Wisconsin) | 566.98 mi (912.46 km) |
| Webster Groves to Surprise (Arizona) | 1,275.27 mi (2,052.34 km) |
| Webster Groves to Susanville (California) | 1,610.22 mi (2,591.40 km) |
| Webster Groves to Sussex (Wisconsin) | 333.37 mi (536.50 km) |
| Webster Groves to Suwanee (Georgia) | 469.53 mi (755.64 km) |
| Webster Groves to Swansea (Illinois) | 20.07 mi (32.29 km) |
| Webster Groves to Sweetwater (Florida) | 1,058.43 mi (1,703.38 km) |
| Webster Groves to Sweetwater (Texas) | 705.17 mi (1,134.86 km) |
| Webster Groves to Sycamore (Illinois) | 251.48 mi (404.72 km) |
| Webster Groves to Sylacauga (Alabama) | 438.25 mi (705.30 km) |
| Webster Groves to Sylvania (Ohio) | 411.81 mi (662.75 km) |
| Webster Groves to Syosset (New York) | 907.53 mi (1,460.53 km) |
| Webster Groves to Syracuse (New York) | 803.00 mi (1,292.31 km) |
