| Weston-super-Mare to Spello | 931.49 mi (1,499.09 km) |
| Weston-super-Mare to Spilamberto | 798.53 mi (1,285.10 km) |
| Weston-super-Mare to Spilimbergo | 805.46 mi (1,296.26 km) |
| Weston-super-Mare to Spinea | 801.11 mi (1,289.26 km) |
| Weston-super-Mare to Spoleto | 943.14 mi (1,517.83 km) |
| Weston-super-Mare to Spoltore | 1,010.92 mi (1,626.92 km) |
| Weston-super-Mare to Spresiano | 793.11 mi (1,276.39 km) |
| Weston-super-Mare to Squinzano | 1,253.86 mi (2,017.90 km) |
| Weston-super-Mare to Statte | 1,215.45 mi (1,956.07 km) |
| Weston-super-Mare to Stezzano | 697.94 mi (1,123.22 km) |
| Weston-super-Mare to Strada | 853.86 mi (1,374.15 km) |
| Weston-super-Mare to Stradella | 710.30 mi (1,143.12 km) |
| Weston-super-Mare to Striano | 1,106.74 mi (1,781.13 km) |
| Weston-super-Mare to Subiaco | 998.44 mi (1,606.84 km) |
| Weston-super-Mare to Sulmona | 1,022.59 mi (1,645.70 km) |
