| Widnes to Sacile | 848.54 mi (1,365.60 km) |
| Widnes to Sala Consilina | 1,238.47 mi (1,993.13 km) |
| Widnes to Salemi | 1,304.37 mi (2,099.18 km) |
| Widnes to Salerno | 1,196.31 mi (1,925.27 km) |
| Widnes to Salo | 798.99 mi (1,285.85 km) |
| Widnes to Salsomaggiore Terme | 821.96 mi (1,322.82 km) |
| Widnes to Saluzzo | 758.25 mi (1,220.29 km) |
| Widnes to Salzano | 855.77 mi (1,377.23 km) |
| Widnes to Samarate | 742.15 mi (1,194.37 km) |
| Widnes to San Benedetto del Tronto | 1,045.90 mi (1,683.22 km) |
| Widnes to San Biagio di Callalta | 857.59 mi (1,380.16 km) |
| Widnes to San Bonifacio | 833.98 mi (1,342.16 km) |
| Widnes to San Casciano in Val di Pesa | 921.71 mi (1,483.35 km) |
| Widnes to San Cataldo | 1,356.80 mi (2,183.57 km) |
| Widnes to San Cesareo | 1,072.43 mi (1,725.91 km) |
