| Winston-Salem to Spello | 4,711.46 mi (7,582.37 km) |
| Winston-Salem to Spilamberto | 4,587.56 mi (7,382.97 km) |
| Winston-Salem to Spilimbergo | 4,614.99 mi (7,427.10 km) |
| Winston-Salem to Spinea | 4,605.30 mi (7,411.51 km) |
| Winston-Salem to Spoleto | 4,720.00 mi (7,596.11 km) |
| Winston-Salem to Spoltore | 4,794.41 mi (7,715.86 km) |
| Winston-Salem to Spresiano | 4,599.55 mi (7,402.27 km) |
| Winston-Salem to Squinzano | 5,040.12 mi (8,111.29 km) |
| Winston-Salem to Statte | 4,997.65 mi (8,042.94 km) |
| Winston-Salem to Stezzano | 4,492.85 mi (7,230.55 km) |
| Winston-Salem to Strada | 4,631.92 mi (7,454.35 km) |
| Winston-Salem to Stradella | 4,495.38 mi (7,234.62 km) |
| Winston-Salem to Striano | 4,871.57 mi (7,840.04 km) |
| Winston-Salem to Subiaco | 4,766.76 mi (7,671.36 km) |
| Winston-Salem to Sulmona | 4,799.33 mi (7,723.77 km) |
