| Winston-Salem to Shoreham-by-Sea | 3,933.96 mi (6,331.10 km) |
| Winston-Salem to Shotley Bridge | 3,791.38 mi (6,101.64 km) |
| Winston-Salem to Shrewsbury | 3,794.86 mi (6,107.24 km) |
| Winston-Salem to Sidcup | 3,936.61 mi (6,335.36 km) |
| Winston-Salem to Sidmouth | 3,813.43 mi (6,137.13 km) |
| Winston-Salem to Sileby | 3,860.72 mi (6,213.23 km) |
| Winston-Salem to Sittingbourne | 3,964.58 mi (6,380.37 km) |
| Winston-Salem to Skegness | 3,910.15 mi (6,292.78 km) |
| Winston-Salem to Skelmersdale | 3,778.77 mi (6,081.35 km) |
| Winston-Salem to Skipton | 3,801.38 mi (6,117.74 km) |
| Winston-Salem to Sleaford | 3,883.15 mi (6,249.32 km) |
| Winston-Salem to Slough | 3,906.58 mi (6,287.04 km) |
| Winston-Salem to Small Heath | 3,835.82 mi (6,173.16 km) |
| Winston-Salem to Smethwick | 3,830.62 mi (6,164.78 km) |
| Winston-Salem to Snaresbrook | 3,929.57 mi (6,324.03 km) |
