| Winston-Salem to Altus (Oklahoma) | 1,075.80 mi (1,731.33 km) |
| Winston-Salem to Alum Rock (California) | 2,284.30 mi (3,676.23 km) |
| Winston-Salem to Alvin (Texas) | 987.55 mi (1,589.30 km) |
| Winston-Salem to Amarillo (Texas) | 1,210.20 mi (1,947.62 km) |
| Winston-Salem to Amelia (Ohio) | 296.37 mi (476.96 km) |
| Winston-Salem to American Canyon (California) | 2,297.76 mi (3,697.89 km) |
| Winston-Salem to American Fork (Utah) | 1,727.16 mi (2,779.60 km) |
| Winston-Salem to Americus (Georgia) | 359.02 mi (577.78 km) |
| Winston-Salem to Ames (Iowa) | 823.96 mi (1,326.04 km) |
| Winston-Salem to Amherst (Ohio) | 381.18 mi (613.45 km) |
| Winston-Salem to Ammon (Idaho) | 1,746.19 mi (2,810.21 km) |
| Winston-Salem to Amsterdam (New York) | 572.32 mi (921.05 km) |
| Winston-Salem to Anacortes (Washington) | 2,293.12 mi (3,690.42 km) |
| Winston-Salem to Anaheim (California) | 2,121.17 mi (3,413.69 km) |
| Winston-Salem to Anchorage (Alaska) | 3,381.78 mi (5,442.45 km) |
