| Winston-Salem to Effingham (Illinois) | 499.08 mi (803.19 km) |
| Winston-Salem to Eggertsville (New York) | 480.50 mi (773.29 km) |
| Winston-Salem to Egypt Lake-Leto (Florida) | 573.84 mi (923.51 km) |
| Winston-Salem to El Cajon (California) | 2,090.94 mi (3,365.05 km) |
| Winston-Salem to El Campo (Texas) | 1,044.54 mi (1,681.03 km) |
| Winston-Salem to El Centro (California) | 2,013.26 mi (3,240.02 km) |
| Winston-Salem to El Cerrito (California) | 2,303.21 mi (3,706.65 km) |
| Winston-Salem to El Dorado (Arkansas) | 731.91 mi (1,177.90 km) |
| Winston-Salem to El Dorado (Kansas) | 922.88 mi (1,485.23 km) |
| Winston-Salem to El Dorado Hills (California) | 2,227.75 mi (3,585.21 km) |
| Winston-Salem to El Mirage (Arizona) | 1,818.31 mi (2,926.29 km) |
| Winston-Salem to El Monte (California) | 2,126.50 mi (3,422.27 km) |
| Winston-Salem to El Paso (Texas) | 1,523.12 mi (2,451.23 km) |
| Winston-Salem to El Paso de Robles (California) | 2,245.30 mi (3,613.46 km) |
| Winston-Salem to El Reno (Oklahoma) | 991.27 mi (1,595.30 km) |
