| Winston-Salem to Lovington (New Mexico) | 1,328.45 mi (2,137.93 km) |
| Winston-Salem to Lowell (Indiana) | 526.47 mi (847.27 km) |
| Winston-Salem to Lowell (Massachusetts) | 656.49 mi (1,056.53 km) |
| Winston-Salem to Lower Burrell (Pennsylvania) | 310.88 mi (500.31 km) |
| Winston-Salem to Lowes Island (Virginia) | 258.33 mi (415.74 km) |
| Winston-Salem to Lubbock (Texas) | 1,236.36 mi (1,989.73 km) |
| Winston-Salem to Lufkin (Texas) | 893.52 mi (1,437.99 km) |
| Winston-Salem to Luling (Louisiana) | 724.25 mi (1,165.57 km) |
| Winston-Salem to Lumberton (North Carolina) | 123.45 mi (198.67 km) |
| Winston-Salem to Lumberton (Texas) | 900.74 mi (1,449.60 km) |
| Winston-Salem to Lutz (Florida) | 564.83 mi (909.01 km) |
| Winston-Salem to Lynbrook (New York) | 475.48 mi (765.21 km) |
| Winston-Salem to Lynchburg (Virginia) | 107.45 mi (172.92 km) |
| Winston-Salem to Lynden (Washington) | 2,288.74 mi (3,683.36 km) |
| Winston-Salem to Lyndhurst (Ohio) | 379.91 mi (611.40 km) |
