| Winston-Salem to Owosso (Michigan) | 519.75 mi (836.45 km) |
| Winston-Salem to Oxford (Alabama) | 361.97 mi (582.53 km) |
| Winston-Salem to Oxford (Mississippi) | 536.71 mi (863.76 km) |
| Winston-Salem to Oxford (Ohio) | 339.32 mi (546.08 km) |
| Winston-Salem to Oxnard (California) | 2,188.07 mi (3,521.36 km) |
| Winston-Salem to Oxon Hill (Maryland) | 258.74 mi (416.40 km) |
| Winston-Salem to Ozark (Alabama) | 445.94 mi (717.67 km) |
| Winston-Salem to Ozark (Missouri) | 721.20 mi (1,160.66 km) |
| Winston-Salem to Pace (Florida) | 549.59 mi (884.49 km) |
| Winston-Salem to Pacific Grove (California) | 2,299.98 mi (3,701.46 km) |
| Winston-Salem to Pacifica (California) | 2,316.47 mi (3,728.00 km) |
| Winston-Salem to Paducah (Kentucky) | 469.70 mi (755.91 km) |
| Winston-Salem to Pahrump (Nevada) | 1,981.93 mi (3,189.61 km) |
| Winston-Salem to Painesville (Ohio) | 392.02 mi (630.90 km) |
| Winston-Salem to Palatine (Illinois) | 588.39 mi (946.92 km) |
