| Winston-Salem to San Luis (Arizona) | 1,971.73 mi (3,173.19 km) |
| Winston-Salem to San Luis Obispo (California) | 2,251.90 mi (3,624.08 km) |
| Winston-Salem to San Marcos (California) | 2,096.34 mi (3,373.74 km) |
| Winston-Salem to San Marcos (Texas) | 1,108.90 mi (1,784.60 km) |
| Winston-Salem to San Marino (California) | 2,130.30 mi (3,428.39 km) |
| Winston-Salem to San Mateo (California) | 2,308.28 mi (3,714.82 km) |
| Winston-Salem to San Pablo (California) | 2,304.84 mi (3,709.28 km) |
| Winston-Salem to San Rafael (California) | 2,314.13 mi (3,724.23 km) |
| Winston-Salem to San Ramon (California) | 2,285.45 mi (3,678.08 km) |
| Winston-Salem to San Tan Valley (Arizona) | 1,783.09 mi (2,869.60 km) |
| Winston-Salem to Sand Springs (Oklahoma) | 884.62 mi (1,423.66 km) |
| Winston-Salem to Sandusky (Ohio) | 391.90 mi (630.70 km) |
| Winston-Salem to Sandy (Oregon) | 2,262.44 mi (3,641.04 km) |
| Winston-Salem to Sandy (Utah) | 1,730.03 mi (2,784.21 km) |
| Winston-Salem to Sandy Springs (Georgia) | 276.49 mi (444.97 km) |
