| Winston-Salem to Savage (Minnesota) | 910.19 mi (1,464.81 km) |
| Winston-Salem to Savannah (Georgia) | 286.40 mi (460.91 km) |
| Winston-Salem to Sayreville (New Jersey) | 440.88 mi (709.52 km) |
| Winston-Salem to Sayville (New York) | 503.59 mi (810.45 km) |
| Winston-Salem to Scaggsville (Maryland) | 279.65 mi (450.05 km) |
| Winston-Salem to Scarsdale (New York) | 486.33 mi (782.67 km) |
| Winston-Salem to Schaumburg (Illinois) | 585.91 mi (942.92 km) |
| Winston-Salem to Schenectady (New York) | 572.72 mi (921.70 km) |
| Winston-Salem to Schererville (Indiana) | 536.26 mi (863.03 km) |
| Winston-Salem to Schertz (Texas) | 1,135.71 mi (1,827.75 km) |
| Winston-Salem to Schiller Park (Illinois) | 574.38 mi (924.38 km) |
| Winston-Salem to Schofield Barracks (Hawaii) | 4,697.71 mi (7,560.24 km) |
| Winston-Salem to Scotchtown (New York) | 488.22 mi (785.71 km) |
| Winston-Salem to Scottdale (Georgia) | 277.10 mi (445.94 km) |
| Winston-Salem to Scotts Valley (California) | 2,298.59 mi (3,699.22 km) |
