| Winston-Salem to Secaucus (New Jersey) | 465.46 mi (749.08 km) |
| Winston-Salem to Security-Widefield (Colorado) | 1,350.05 mi (2,172.69 km) |
| Winston-Salem to Sedalia (Missouri) | 733.68 mi (1,180.75 km) |
| Winston-Salem to Sedro-Woolley (Washington) | 2,275.21 mi (3,661.60 km) |
| Winston-Salem to Seguin (Texas) | 1,119.79 mi (1,802.12 km) |
| Winston-Salem to Selden (New York) | 510.35 mi (821.32 km) |
| Winston-Salem to Selma (Alabama) | 462.89 mi (744.95 km) |
| Winston-Salem to Selma (California) | 2,174.98 mi (3,500.29 km) |
| Winston-Salem to Selma (Texas) | 1,138.18 mi (1,831.72 km) |
| Winston-Salem to Seminole (Florida) | 589.45 mi (948.62 km) |
| Winston-Salem to Seven Hills (Ohio) | 372.48 mi (599.45 km) |
| Winston-Salem to Seven Oaks (South Carolina) | 150.52 mi (242.25 km) |
| Winston-Salem to Severn (Maryland) | 286.27 mi (460.70 km) |
| Winston-Salem to Severna Park (Maryland) | 288.69 mi (464.59 km) |
| Winston-Salem to Sevierville (Tennessee) | 185.44 mi (298.44 km) |
