| Winston-Salem to Shelbyville (Tennessee) | 349.36 mi (562.24 km) |
| Winston-Salem to Shelton (Connecticut) | 525.70 mi (846.04 km) |
| Winston-Salem to Shelton (Washington) | 2,308.16 mi (3,714.62 km) |
| Winston-Salem to Shenandoah (Louisiana) | 734.34 mi (1,181.81 km) |
| Winston-Salem to Shepherdsville (Kentucky) | 326.80 mi (525.93 km) |
| Winston-Salem to Sheridan (Wyoming) | 1,518.16 mi (2,443.25 km) |
| Winston-Salem to Sherman (Texas) | 941.98 mi (1,515.96 km) |
| Winston-Salem to Sherrelwood (Colorado) | 1,367.46 mi (2,200.71 km) |
| Winston-Salem to Sherwood (Arkansas) | 677.03 mi (1,089.58 km) |
| Winston-Salem to Sherwood (Oregon) | 2,290.18 mi (3,685.69 km) |
| Winston-Salem to Shiloh (Illinois) | 556.50 mi (895.61 km) |
| Winston-Salem to Shiloh (Ohio) | 335.49 mi (539.91 km) |
| Winston-Salem to Shiloh (Pennsylvania) | 327.27 mi (526.68 km) |
| Winston-Salem to Shirley (New York) | 514.24 mi (827.58 km) |
| Winston-Salem to Shively (Kentucky) | 338.21 mi (544.30 km) |
