| Winston-Salem to Shoreline (Washington) | 2,275.13 mi (3,661.47 km) |
| Winston-Salem to Shoreview (Minnesota) | 915.18 mi (1,472.83 km) |
| Winston-Salem to Shorewood (Illinois) | 568.14 mi (914.33 km) |
| Winston-Salem to Shorewood (Wisconsin) | 630.27 mi (1,014.32 km) |
| Winston-Salem to Short Hills (New Jersey) | 453.39 mi (729.66 km) |
| Winston-Salem to Short Pump (Virginia) | 181.10 mi (291.45 km) |
| Winston-Salem to Show Low (Arizona) | 1,679.74 mi (2,703.29 km) |
| Winston-Salem to Shreveport (Louisiana) | 811.68 mi (1,306.27 km) |
| Winston-Salem to Sicklerville (New Jersey) | 381.65 mi (614.21 km) |
| Winston-Salem to Sidney (Ohio) | 358.57 mi (577.06 km) |
| Winston-Salem to Sierra Madre (California) | 2,126.02 mi (3,421.50 km) |
| Winston-Salem to Sierra Vista (Arizona) | 1,746.02 mi (2,809.94 km) |
| Winston-Salem to Sierra Vista Southeast (Arizona) | 1,742.92 mi (2,804.96 km) |
| Winston-Salem to Signal Hill (California) | 2,139.03 mi (3,442.44 km) |
| Winston-Salem to Sikeston (Missouri) | 520.66 mi (837.91 km) |
