| Winston-Salem to Somerset (New Jersey) | 435.90 mi (701.52 km) |
| Winston-Salem to Somersworth (New Hampshire) | 701.02 mi (1,128.18 km) |
| Winston-Salem to Somerton (Arizona) | 1,969.00 mi (3,168.80 km) |
| Winston-Salem to Somerville (Massachusetts) | 654.24 mi (1,052.89 km) |
| Winston-Salem to Somerville (New Jersey) | 434.63 mi (699.47 km) |
| Winston-Salem to Sonoma (California) | 2,307.26 mi (3,713.18 km) |
| Winston-Salem to Soquel (California) | 2,295.93 mi (3,694.95 km) |
| Winston-Salem to South Bend (Indiana) | 502.44 mi (808.60 km) |
| Winston-Salem to South Bradenton (Florida) | 612.39 mi (985.54 km) |
| Winston-Salem to South Burlington (Vermont) | 685.91 mi (1,103.86 km) |
| Winston-Salem to South Charleston (West Virginia) | 174.21 mi (280.36 km) |
| Winston-Salem to South Daytona (Florida) | 481.26 mi (774.52 km) |
| Winston-Salem to South El Monte (California) | 2,128.00 mi (3,424.69 km) |
| Winston-Salem to South Elgin (Illinois) | 592.95 mi (954.25 km) |
| Winston-Salem to South Euclid (Ohio) | 380.67 mi (612.64 km) |
