| Winston-Salem to Steiner Ranch (Texas) | 1,091.51 mi (1,756.61 km) |
| Winston-Salem to Stephenville (Texas) | 1,059.63 mi (1,705.30 km) |
| Winston-Salem to Sterling (Colorado) | 1,276.94 mi (2,055.03 km) |
| Winston-Salem to Sterling (Illinois) | 641.14 mi (1,031.82 km) |
| Winston-Salem to Sterling (Virginia) | 254.30 mi (409.26 km) |
| Winston-Salem to Sterling Heights (Michigan) | 471.34 mi (758.55 km) |
| Winston-Salem to Steubenville (Ohio) | 295.27 mi (475.18 km) |
| Winston-Salem to Stevens Point (Wisconsin) | 759.28 mi (1,221.94 km) |
| Winston-Salem to Stevenson Ranch (California) | 2,151.94 mi (3,463.22 km) |
| Winston-Salem to Stillwater (Minnesota) | 902.40 mi (1,452.27 km) |
| Winston-Salem to Stillwater (Oklahoma) | 937.24 mi (1,508.35 km) |
| Winston-Salem to Stockbridge (Georgia) | 286.99 mi (461.87 km) |
| Winston-Salem to Stockton (California) | 2,249.30 mi (3,619.90 km) |
| Winston-Salem to Stone Ridge (Virginia) | 245.17 mi (394.56 km) |
| Winston-Salem to Stonecrest (Georgia) | 275.97 mi (444.13 km) |
