| Winston-Salem to University Park (Texas) | 966.78 mi (1,555.88 km) |
| Winston-Salem to University Place (Washington) | 2,281.64 mi (3,671.94 km) |
| Winston-Salem to Upland (California) | 2,105.32 mi (3,388.19 km) |
| Winston-Salem to Upper Arlington (Ohio) | 311.20 mi (500.83 km) |
| Winston-Salem to Upper Grand Lagoon (Florida) | 518.05 mi (833.73 km) |
| Winston-Salem to Upper Montclair (New Jersey) | 463.17 mi (745.41 km) |
| Winston-Salem to Urbana (Illinois) | 512.37 mi (824.57 km) |
| Winston-Salem to Urbana (Maryland) | 273.98 mi (440.93 km) |
| Winston-Salem to Urbana (Ohio) | 335.58 mi (540.07 km) |
| Winston-Salem to Urbandale (Iowa) | 820.42 mi (1,320.34 km) |
| Winston-Salem to Utica (New York) | 552.30 mi (888.83 km) |
| Winston-Salem to Uvalde (Texas) | 1,228.11 mi (1,976.46 km) |
| Winston-Salem to Vacaville (California) | 2,280.15 mi (3,669.55 km) |
| Winston-Salem to Vadnais Heights (Minnesota) | 911.67 mi (1,467.20 km) |
| Winston-Salem to Vail (Arizona) | 1,757.28 mi (2,828.07 km) |
