| Wuppertal to Santeramo in Colle | 855.31 mi (1,376.49 km) |
| Wuppertal to Santo Stefano di Magra | 506.92 mi (815.81 km) |
| Wuppertal to Santo Stino di Livenza | 457.50 mi (736.28 km) |
| Wuppertal to Sarezzo | 411.87 mi (662.83 km) |
| Wuppertal to Sarno | 804.26 mi (1,294.33 km) |
| Wuppertal to Saronno | 398.89 mi (641.94 km) |
| Wuppertal to Sarzana | 510.73 mi (821.93 km) |
| Wuppertal to Sassari | 731.20 mi (1,176.75 km) |
| Wuppertal to Sasso Marconi | 510.36 mi (821.34 km) |
| Wuppertal to Sassuolo | 492.89 mi (793.23 km) |
| Wuppertal to Sava | 900.04 mi (1,448.47 km) |
| Wuppertal to Saviano | 795.84 mi (1,280.77 km) |
| Wuppertal to Savigliano | 457.64 mi (736.50 km) |
| Wuppertal to Savignano sul Panaro | 501.32 mi (806.80 km) |
| Wuppertal to Savignano sul Rubicone | 551.70 mi (887.88 km) |
